Jane Mellor is a member of the Department of Biochemistry at Oxford University, where she is currently Director of Teaching. She held research fellowships at Wolfson College and Exeter College before becoming Tutor in Biochemistry at The Queen’s College in 1995. She has served as Equalities Officer, Tutor for Graduates and Dean.
After a PhD working on foot and mouth disease virus at the Animal Virus Research Institute in Pirbright and a post-doc developing technologies with the first biotechnology companies in the UK, she established her research group in Oxford to focus on gene expression, chromatin, and metabolism. Recently, the group has pioneered our understanding of the dark genome, demonstrating roles for the non-coding transcriptome in switching chromosome conformation signatures to coordinate gene expression with metabolism and to altering chromatin structure over genes. Lately, the group had applied mathematical modelling to uncover fundamental relationships in transcription and RNA biology that are beyond the resolution of current experimental techniques. Her research is currently funded by the EU (PEP:NET and Cell2Cell) and BBSRC (UK) and has contributed to two successful spin-out companies: Oxford BioDynamics plc and Sibelius Natural Products Ltd. She was elected a member of EMBO in 2010.